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Pesticides, heated plastic and commercially raised animal products. These are wrecking havoc on our hormones, skin, mood, and waistlines in both men and women. Diindoylymethane (DIM) has potent effects on Estrogen metabolism, it can inhibit the aromatase enzyme, prevent conversion of testosterone into Estrogen and act on more potent forms of Estrogen and convert them into less potent forms; this conversion reduces the overall effects of Estrogen in the body. BioPerine® is a standardized Piperine composition derived from Black Pepper Extract and has been shown in clinical research to increase the absorption of nutrients in nutritional supplement formulations. In general, it was found to enhance absorption of nutrients by at least 30%. Broccoli Extract contains many phytochemicals that promote healthy metabolism of hormones, thereby reducing the negative side effects associated with Estrogen dominance. Calcium D-Glucarate works by metabolizing an excess of Estrogen in the body and helps the liver to metabolize hormones which is necessary for both males and females.