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VetGuard Plus Flea and Tick Control for Medium Dogs kills fleas, flea eggs and larvae, lice and ticks and repels new fleas, ticks and mosquitoes for up to four weeks. The package includes four monthly applications for use on dogs between 16 and 33 pounds. VetGuard Plus for Dogs provides two active ingredients that work together to keep pesky invaders off and away from your dog. Permethrin – a powerful, fast-acting insecticide that kills and repels adult fleas, lice, ticks, and other invaders for up to four weeks with just one application. And, Pyriproxyfen (Nylar) – an insect growth regulator that targets and destroys flea larvae, keeping future generations off your dog. EPA Reg # 67505-3-88966