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The Breakthrough: Immunotherapy and the Race to Cure Cancer
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About The Breakthrough: Immunotherapy And The Race To
Product Description Charles Graeber, New York Times bestselling author of The Good Nurse, details the astonishing scientific discovery of the code to unleashing the human immune system to fight -- and possibly even cure -- cancer, featuring interviews with 2018 Nobel Prize in Medicine award-winners James P. Allison and Tasuku Honjo. For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses-tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step-harnessing the wealth of new information to create modern and more effective patient therapies-is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history. Review "Deft, detailed...fascinating. From the once-discredited pioneer William Coley to immunologist and Nobel laureate James P. Allison, (the characters) form a brilliant, driven, admirably stubborn group that Graeber brings vividly to life." - Nature " Exciting reading. " - Booklist "Lucid and informed...Graeber gives readers a basis for both understanding the challenges involved and for cautious optimism that a cure can be found." ―Publishers Weekly "F ascinating...(Graeber is) a gifted narrative writer who takes on medical matters with sophistication and clarity." - The National Book Review "A great book. A must-read".-Dr. James L. Gulley M.D. Ph.D., Director, Medical Oncology Service, National Cancer Institute (NCI)"Fascinating...An untold story..that Siddhartha Mukherjee's 2010 'The Emperor of All Maladies'...barely even acknowledged."-The New York Times Book Review (An "Editor's Choice" Book) "If you or a loved one has cancer, this is a book you'll want to pick up."-Dana Perino, FOX Nation"Gripping. Riveting. A terrific Book."-The Washington Post"This is your new survival manual."--William Ferrall, Mahon About Town"Gift this to partners, children, parents and friends."-Carolyn Wong Simpkins, Science Magazine"Brilliant. Reads like a crime thriller because that's what it is. "-Financial Review"Extraordinary."-The Sydney Morning Herald"Rare and thrilling...a hopeful, even inspiring, book about cancer."-Chris Hewitt, Minneapolis Star Tribune "Fantastic."-Wired ("Top Science Books")"Brilliantly rendered..terrific, compelling...pulls you into the narrative right off the hop and never lets go."-Douglas J. Johnston, Winnipeg Free Press"Fascinating" --The National Book Review "Five Hot Books""Crisp and suspenseful...the perfect backstory for this year's Nobel Prize in Medicine."- Jane Ciabattari, BBC "Ten Books to Read This Month""Lucid and informed."--Publishers Weekly"Exciting reading"--Booklist"Fascinating, well-researched
