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This herb has been used in traditional Chinese medicine for over two thousand years. It contains a number of alkaloids such as 5-7% berberine as well as other important therapeutic compounds such as coptisine. It has been used extensively in the treatment of gastrointestinal troubles. It is also reported to have anti-radiation effects. In a situation where you have an “over facilitated sympathetic nervous system” it has been shown to be helpful. Golden Thread Supreme is packaged in a bottle containing 60 veggie capsules, each containing approximately 545 mg of powdered Coptis chinensis rhizome without fillers, binders or excipients. Recommended Use: 1 capsule 3x per day.