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Silver, which occurs naturally in mushrooms, whole grains, water, and mammalian milk, has been used for centuries to safeguard human health. In 400 B.C. Hippocrates, the father of medicine, wrote of the healing properties of silver. In the middle ages, wealthy families fed their children with silver utensils (that's where the phrase "born with a silver spoon" comes from!). Today, NASA uses silver to purify water on the International Space Station and silver-based products are widely used in burn units around the globe. Colloidal silver is having its resurgence for immune support. SAFE & EFFECTIVE: The EPA has an established Daily Oral Reference Dose (RfD) for Silver of 350 micrograms of Silver (µAg) Many brands don't readily share this information because they know that their products far exceed this amount by upwards of 400% in one dose. It is safe to take 1 tsp of Sovereign Silver 7x/day for 70 years and still be within the EPA RfD. However, you can only take 1/4 tsp (of the 1 tsp daily dose) of a competitor's 250 ppm product before you reach the RfD. Less is certainly more in this case! Active concentration matters, not total concentration: Small particle size yields greater surface area, which through oxidation creates more positively charged silver. The larger the particle, the greater the amount of waste that your body must figure out how to excrete. It's this excess silver that can be toxic and potentially cause side effect such as Argyria, a benign condition that turns the skin blue. Think of it like trying to get rocks through an hourglass compared to sand. Sovereign Silver's unprecedented small particle size makes it easy for the body to absorb and excrete. Natural Immunogenics is an NSF Registered GMP (Good Manufacturing Process) manufacturer.