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These high efficiency particulate air (HEPA) filters are 99.97% efficient against particles which are at 0.3 microns (about 300x smaller than the diameter of human hair) or larger; Designed with pleats, these patented cartridges feature a large surface area in a very small diameter, low-profile cartridge; This low profile gives the Toxic Dust Replacement Cartridges the benefit of being out of the way of users when attached to the respirator body; This model of cartridge is a direct replacement for the Toxic Dust Respirator's (model # 817664) cartridges