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Preparation H Suppositories soothe, protect, and get you back to your regularly scheduled day. These hemorrhoid suppositories promptly and effectively relieve painful burning, anus itching and discomfort. Using Preparation H Suppositories at night can help you rest comfortably while it reduces internal swelling caused by hemorrhoids. While you can't get rid of hemorrhoids completely, you can relieve symptoms of a flare up with hemorrhoid suppositories. In fact, treating uncomfortable symptoms of hemorrhoids at the first sign can help prevent further irritation. You can get additional relief by using Preparation H Medicated Wipes to cool, soothe and cleanse external hemorrhoid symptoms before treating internal hemorrhoids.