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The Powerpuff Girls: Paint the Townsville Green features brawny Buttercup, who fights and destroys enemies, while the other two girls are in reserve for superattacks. The side-scrolling game has multiscreen maps in which our hero dodges obstacles, collects power-ups, destroys enemies, rescues friends, and ultimately fights the featured villains to save Townsville. The villainous Gangrene Gang and Fuzzy Lumpkins use brute force, and can only be answered in kind. Players can collect and trade electronic game cards with a friend's copy of the game via the separately sold Game Boy link cable, as well as engage in two-player head-to-head action. Use secret passwords to unlock new game features, including trading cards and hidden powers.