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Supports the wrist and thumb, leaving the palm free. Three removable metal splints in thumb area for improved stability. Additional strap for stabilization during activities. Ideal for sprains of thumb, ligament support, and minor fractures of the thumb. Application: De Quervain's disease, Thumb sprain/strain, CMC joint injury and Thumb pain 70% Coolprene, 15% Nylon, 15% Cotton Sizing (measure the circumference of your wrist): Small: 13.0-15.2cm (5 1/8 - 6") Medium: 15.2-17.2cm (6 - 6 3/4") Large: 17.2-19.1cm (6 3/4 - 7 1/2") XLarge: 19.1-21.0cm (7 1/2 - 8 1/4")