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Measure around the ankle joint: S: 6 1/8 - 8 ¼ inches (15.6 - 21.0 cm); M: 8 1/4 - 10 ¼ inches (21.0 - 26.0 cm); L: 10 1/4 - 12 ¼ inches (26.0 - 31.1 cm); XL: 12 1/4 - 14 ¼ inches (31.1 - 36.2 cm). OPPO Medical offers the most extensive range of functional supports with uncompromising quality, a keen understanding of the rehabilitation market and a passion for innovation. For your continued health, we are expanding the frontiers of orthopedic medicine with innovative materials and designs and a holistic approach to wellness.