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Product Description A healthy cholesterol level is an important part of heart health.(1) CholestOff Plus is formulated with esterified sterols and stanols instead of free form sterols and stanols that are formulated in CholestOff Original. The esterified sterols and stanols have been clinically proven to have cholesterol-lowering benefits.(1) Additionally, Nature Made has conducted clinical trials examining the effects of CholestOff Plus on cholesterol. Our studies show that consuming CholestOff Plus in addition to following the National Institutes of Health's National Cholesterol Education Program (NCEP) Therapeutic Lifestyle Changes (TLC) diet, reduced LDL cholesterol levels.(1) (1)Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of Nature Made CholestOff Plus supplies 900 mg of plant sterols and stanols for a daily intake of 1,800 mg. Brand Story By Nature Made