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These nozzles range in size to allow the perfect, precise targeting of warts, skin tags, or moles. Four diameters are included: 2mm, 3mm, 4mm, and 5mm. The nozzles can be washed and reused for repeated treatment. To use, simply place the narrow end of one of the nozzles against the skin such that the wart or skin tag is fully enclosed by the hole in the nozzle. These nozzles essentially act as a mask to prevent overspray from freeze spray products onto healthy skin. It's recommended to use a size slightly larger than the diameter of the skin blemish so that some of the surrounding skin is frozen (prevents partial treatment of the wart or skin tag). Alternatively, place a cotton ball inside of the nozzle and push it through so that it slightly pokes out of the narrow side. Apply freeze spray to the wide side and allow it to work its way towards the narrow end. Once the tip of cotton sticking out is adequately chilled, "paint" the treatment area with it. Continue apply freeze spray as required to keep the cotton cold enough to cause blistering of treated areas.