600401-108-0.1 - Size : 100 micrograms - Anti-COL6A1 Rabbit Polyclonal Antibody - Each (100micrograms)

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600401-108-0.1 - Size : 100 micrograms Features

• Size : 100 micrograms

• Supplier No. : 600401-108-0.1

About 600401-108-0.1 - Size : 100 Micrograms

Rockland produces highly active antibodies and conjugates to collagens. Collagens are highly conserved throughout evolution and are characterized by an uninterrupted ''Glycine-X-Y'' triplet repeat that is a necessary part of the triple helical structure. For these reasons, it is often extremely difficult to generate antibodies with specificities to collagens. The development of ‘type†specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. Rockland extensively purifies collagens for immunization from human and bovine placenta and cartilage by limited pepsin digestion and selective salt precipitation. This preparation results in a native conformation of the protein. Antibodies are isolated from rabbit antiserum and are extensively cross-adsorbed by immunoaffinity purification to produce 'type' specific antibodies. Greatly diminished reactivity and selectivity of these antibodies will result if denaturing and reducing conditions are used for SDS-PAGE and immunoblotting. Anti-Collagen antibodies have been used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, immunoprecipitation, native (non-denaturing, non-dissociating) PAGE, immunohistochemistry, and western blotting for highly sensitive qualitative analysis. Type: PrimaryAntigen: COL6A1Clonality: PolyclonalClone: Conjugation: Epitope: Host: RabbitIsotype: Reactivity: