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Nitric Oxide Boost is the Pump-Up-Your-Muscles secret weapon for athletes! It combines the amino acids L-Citrulline and L-Arginine to help support nitric oxide production.* L-Arginine is known for its "pump" effect due to its role in the synthesis of nitric oxide. It is the main substrate (precursor) in the reaction to produce nitric oxide. When the body produces nitric oxide, the diameter of the blood vessels increase, which increases blood flow. This results in an enhanced muscle pump plus the potential for increased exercise capacity, endurance and recovery.* L-Citrulline is closely related to L-arginine in structure. It is an amino acid that is also involved in nitric oxide synthesis. When ingested, L-citrulline is not broken down by the liver before entering the bloodstream like L-arginine is, so more is available for the body to use. Instead, it is metabolized by the kidneys into L-arginine. It has been shown to increase blood plasma levels of L-arginine better than taking L-arginine itself.* But according to some researchers, even more effective than taking L-citrulline is a combination of L-arginine and L-citrulline. L-citrulline has also been show to inhibit arginase, the enzyme that breaks down L-arginine. As a result, scientists speculate that taking L-citrulline with L-arginine may help more of the ingested L-arginine pass through the liver intact to the bloodstream.* We also include SpectraTM, a precise blend of 29 fruit, vegetable and herbal ingredients. SpectraTM was shown in a clinical trial to help support nitric oxide levels and antioxidant activity in humans at a dose of 100 mg.* In the body, nitric oxide plays a role in aerobic capacity, exercise performance and cardiovascular health.*