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Arthri-Flex Advantage with Vitamin D3 is the latest development in joint support formulas from studies on joint nutrition science. Arthri-Flex Advantage plus Vitamin D3 combines Glucosamine Sulfate and MSM(Methylsulfonylmethane) with FLEXICOL (a blend of premium Type II Chicken Sternum Collagen [containing naturally occurring Chondroitin Sulfate], Hyaluronic Acid and other synergistic herbal extracts and mineral compounds) to support both joints and cartilage. And now with Vitamin D3 to support normal bone health.