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To create Biofreeze Professional, we started with the original Biofreeze formula and optimized key ingredients based on scientific research for a longer-lasting experience. Biofreeze Professional also offers easier application with a smoother consistency. It is an effective, non-systemic solution for pain relief during patient office visits and for use by patients at home between visits. Biofreeze Professional uses cold therapy to relieve pain from backaches, arthritis, sore muscles and joints, sprains, and more.